{p=1. Through the design of this single-side salt-freezing–drying–wetting cycle test method more truly reflects the impact of the service environment on concrete (ordinary concrete, basalt fiber reinforced concrete). 2. Through the comparative study of macroscopic mechanical properties and microstructure, the failure mechanism of concrete (ordinary concrete, basalt fiber reinforced concrete) and the main strengthening mechanism of basalt fiber under single-side salt-freezing–drying–wetting cycle were revealed. 3. The correlation calculation proves that the mechanical properties of concrete (ordinary concrete, basalt fiber reinforced concrete) are highly correlated with porosity, pore size distribution and critical pore size under single-side salt-freezing–drying–wetting cycle. 4. The sensitive aperture of compressive strength and splitting tensile strength of concrete (ordinary concrete, basalt fiber reinforced concrete) under single-side salt-freezing–drying–wetting cycle is calculated, which provides a reference for further comprehensive analysis and calculation., h1=Highlights}

{p=Many L2 learners preparing for high-stakes, on-demand English language tests (e.g., IELTS, TOEFL) undertake classroom-based test preparation involving the provision of teacher written feedback commentary (WFC) on writing that simulates test tasks. The assumption is teachers’ knowledge of both the language and testing system helps develop candidates’ language/test-taking skills and familiarity with task expectations. Prior research has indicated features of WFC’s content and delivery can impact on the extent and quality of student revisions, although preparation for writing assessment settings have yet to be explored. The present study investigated the effects of five WFC content and delivery characteristics (focus, length, explicitness, semantic function, and presence of mitigation) on three rehearsal essays written by eight candidates preparing for IELTS Writing Task 2. The qualities of content and delivery most associated with substantive, positive revisions included comments targeting Task Response, those 50 words or longer, when an explicit revision strategy was provided, the presence of mitigation through personal attribution, and question posing and criticism. The study found learners tended not to act upon descriptive end comments explicating written performance, praise, and comments below five words in length. The implications for teachers in classroom IELTS preparation contexts are discussed., h1=Abstract}

{p=[Aim, The purpose of our study was to review a large cohort of athletes of all levels presenting with groin pain who underwent investigation with MRI and to determine what the commonest patterns of injury were. We aimed to explore whether particular findings were commonly found in association and whether measurable gender differences exist in the incidence of specific injuries., Materials and methods, Imaging records were reviewed to identify MRI studies of the pelvis performed for the investigation of groin pain in patients who were active in sports/athletic pursuits. Findings were classified and recorded as follows: injury to the common rectus abdominis/adductor longus origin, injury to the short adductor muscles, pubic bone oedema, pubic symphysis degenerative changes, hip joint injury and ‘other’. The prevalence of specific injuries in female athletes compared to males was analysed using relative risk ratios., Results, A total of 470 athletes underwent MRI for the investigation of groin pain during the study period. Forty-six were female, and 424 were male. Female athletes were significantly less likely to have rectus abdominis-adductor longus (RR = 0.31, p  = .017), short adductor (RR = 0.14, p  = .005) or hip (RR = 0.41, p  = .003) injuries. Pubic bone degenerative changes were much more common in female athletes (RR = 7.37, p  = .002)., Conclusion, Significant gender differences exist in the frequency with which specific injuries are observed. Female athletes are also significantly underrepresented; this is likely a multifactorial phenomenon; however, the possibility of unconscious referrer bias must be considered.], h1=Abstract}

{p=[Background, To evaluate the stiffness of the tunica albuginea (TA), we used a new noninvasive diagnostic technique called shear wave elastography (SWE). We determined whether SWE values are correlated with the degree of penile curvature, the time of disease onset, and pain severity experienced by patients during erection. This study analyzed the elasticity of the TA of patients with Peyronie’s disease compared to that of the control group. We also analyzed any correlations between the stiffness of the cavernous bodies and the degree of curvature, time from diagnosis to curvature onset, and erectile pain severity. This was a prospective case–control study involving 100 men enrolled from September 2020 to August 2021. Participants were divided into group A (case group, n  = 50), which included men with PD, with or without pain, and with penile curvature, or group B (control group, n  = 50), which included healthy patients older than 18 years who visited the urology clinic for reasons other than PD. The medical history was collected for all patients who also underwent objective examination, B-mode ultrasound evaluation, and SWE. The International Index of Erectile Function (IIEF-15) visual analog scale (VAS) questionnaire was administered to all participants., Results, There were no significant between-group differences regarding age, weight, and height ( p  > 0.05); however, there was a significant difference in the stiffness values ( p  < 0.05). An inverse correlation was observed between stiffness and the VAS score ( p  < 0.0001). A positive correlation was observed between the degree of curvature ( p  < 0.0001) and the time of curvature onset ( p  < 0.0001). The IIEF-15 scores were poorer in group A than in group B ( p  < 0.0001)., Conclusion, SWE is an inexpensive, noninvasive method that can be used to measure the stiffness of PD patients., Contexte, Pour évaluer la rigidité de la tunique albuginée (TA), nous avons utilisé une nouvelle technique de diagnostic non invasive, appelée élastographie par ondes de cisaillement (EOC). Nous avons déterminé si les valeurs de EOC étaient corrélées avec le degré de courbure du pénis, le moment d’apparition de la maladie de Lapeyronie (MP) et la gravité de la douleur ressentie par les patients pendant l’érection. Cette étude a analysé l’élasticité de la TA des patients atteints de MP par rapport à celle d’un groupe témoin. Nous avons également recherché toute corrélation entre la rigidité des corps caverneux et le degré de courbure, le temps écoulé entre le diagnostic et l’apparition de la courbure, et la gravité de la douleur érectile. Il s’agit d’une étude cas-témoins prospective impliquant 100 hommes enrôlés de septembre 2020 à août 2021. Les participants ont été assignés au groupe A (cas, n = 50), qui comprenait des hommes atteints de MP, avec ou sans douleur, et présentant une courbure du pénis, ou au groupe B (témoins, n = 50), qui comprenait des patients en bonne santé âgés de plus de 18 ans qui venaient à la clinique d’urologie pour des raisons autres que la MP. Les antécédents médicaux ont été recueillis pour tous les patients qui ont également subi un examen objectif, une évaluation échographique en mode B et une EOC. Le questionnaire de l’échelle visuelle analogique (EVA) de l’Indice international de la fonction érectile (IIEF-15) a été administré à tous les participants., Résultats, Il n’y avait pas de différences significatives entre les groupes en ce qui concerne l’âge, le poids et la taille ; toutefois, il y avait une différence significative dans les valeurs de rigidité (p<0,05). Une corrélation inverse a été observée entre la rigidité et le score EVA (p<0,0001). Une corrélation positive a été observée entre le degré de courbure (p<0,0001) et le moment de l’apparition de la courbure (p<0,0001). Les scores IIEF-15 étaient plus faibles dans le groupe A que dans le groupe B (p<0,0001)., Conclusions, L’élastographie par ondes de cisaillement (EOC) est une méthode peu coûteuse et non invasive qui peut être utilisée pour mesurer la rigidité des patients atteints de MP.], h1=Résumé}

{p=[Background, Organ function is known to decline with age. Optimizing cardiac, pulmonary and renal function in older adults has led to significant improvements in perioperative care. However, when substantial blood loss and fluid shifts occur, perioperative outcomes still remains poor, especially in older adults. We suspect that this could be due to age-related changes in endothelial function—an organ controlling the transport of fluid and solutes. The capillary filtration coefficient (CFC) is an important determinant of fluid transport. The CFC can be measured in vivo, which provides a tool to estimate endothelial barrier function. We have previously shown that the CFC increases when giving a fluid bolus resulting in increased vascular and extravascular volume expansion, in young adults. This study aimed to compare the physiologic determinants of fluid distribution in young versus older adults so that clinicians can best optimize perioperative fluid therapy., Methods, Ten healthy young volunteers (ages 21–35) and nine healthy older volunteers (ages 60–75) received a 10 mL/kg fluid bolus over the course of twenty minutes. Hemodynamics, systolic and diastolic heart function, fluid volumetrics and microcirculatory determinants were measured before, during, and after the fluid bolus., Results, Diastolic function was reduced in older versus younger adults before and after fluid bolus ( P  < 0.01). Basal CFC and plasma oncotic pressure were lower in the older versus younger adults. Further, CFC did not increase in older adults following the fluid bolus, whereas it did in younger adults ( p  < 0.05). Cumulative urinary output, while lower in older adults, was not significantly different ( p  = 0.059). Mean arterial pressure and systemic vascular resistance were elevated in the older versus younger adults ( p  < 0.05)., Conclusion, Older adults show a less reactive CFC to a fluid bolus, which could reduce blood to tissue transport of fluid. Diastolic dysfunction likely contributes to fluid maldistribution in older adults.], h1=Abstract}

{p=[Purpose, Biosynthesis of nanoparticles is an eco-friendly process and considered one of the most significant aspects of nanotechnology. Silver nanoparticles (Ag NPs) have a better bactericidal activity due to its high surface area to volume ratio. In this paper, Streptomyces sp. U13 (KP109813) was used to biosynthesize silver nanoparticles (Ag NPs) to construct wastewater disinfection filter., Methods, The biosynthesized nanosilver and a commercially available ink nanosilver were characterized, and their wastewater disinfection efficiency was compared. The nanometrological characteristics of both nanosilver such as structure, shape, and size were investigated using the X-ray diffraction (XRD), Fourier transform-infrared spectroscopy (FTIR), high-resolution transmission electron microscope (HR-TEM), and UV-visible spectroscopy., Result, The results revealed that the biosynthesized and ink Ag NPs were well dispersed and had a spherical shape, with sizes ranged from 5 to 37 nm and from 2 to 26 nm, respectively. To examine the disinfection capabilities, Ag NPs were loaded on two substrates, foam and limestone gravel, and packed into a glass column receiving domestic wastewater. Results showed that Ag NPs attached to limestone gravel eliminate 100% of the coliform bacteria better than foam. Comparing to control columns (without silver), only 50 and 10% reduction of the total coliform in gravel and foam column were achieved, respectively., Conclusion, This work concluded that the type of substrate controls the amount of Ag NPs loaded on it and thus controls the disinfection process. No significant difference between biosynthesized and ink nanosilver in wastewater disinfection was observed. Using limestone gravel filter loaded with 200 mg/l Ag NPs with contact time of 150 min achieves a complete eradication of coliform bacteria.], h1=Abstract}

{p=An increasing number of large-scale multi-modal research initiatives has been conducted in the typically developing population, e.g. Dev. Cogn. Neur. 32:43-54, 2018; PLoS Med. 12(3):e1001779, 2015; Elam and Van Essen, Enc. Comp. Neur., 2013, as well as in psychiatric cohorts, e.g. Trans. Psych. 10(1):100, 2020; Mol. Psych. 19:659–667, 2014; Mol. Aut. 8:24, 2017; Eur. Child and Adol. Psych. 24(3):265–281, 2015. Missing data is a common problem in such datasets due to the difficulty of assessing multiple measures on a large number of participants. The consequences of missing data accumulate when researchers aim to integrate relationships across multiple measures. Here we aim to evaluate different imputation strategies to fill in missing values in clinical data from a large (total N  = 764) and deeply phenotyped (i.e. range of clinical and cognitive instruments administered) sample of N  = 453 autistic individuals and N  = 311 control individuals recruited as part of the EU-AIMS Longitudinal European Autism Project (LEAP) consortium. In particular, we consider a total of 160 clinical measures divided in 15 overlapping subsets of participants. We use two simple but common univariate strategies—mean and median imputation—as well as a Round Robin regression approach involving four independent multivariate regression models including Bayesian Ridge regression, as well as several non-linear models: Decision Trees (Extra Trees., and Nearest Neighbours regression. We evaluate the models using the traditional mean square error towards removed available data, and also consider the Kullback–Leibler divergence between the observed and the imputed distributions. We show that all of the multivariate approaches tested provide a substantial improvement compared to typical univariate approaches. Further, our analyses reveal that across all 15 data-subsets tested, an Extra Trees regression approach provided the best global results. This not only allows the selection of a unique model to impute missing data for the LEAP project and delivers a fixed set of imputed clinical data to be used by researchers working with the LEAP dataset in the future, but provides more general guidelines for data imputation in large scale epidemiological studies., h1=Abstract}